A peripheral comment

Comment on “Reelin Promotes Peripheral Synapse Elimination

Individual synaptic sites on rodent skeletal muscle fibers are innervated by two or more axons at birth. All inputs but one are then eliminated during the first two postnatal weeks, leaving each muscle fiber singly innervated (1). Quattrocchi et al. (2) reported that polyneuronal innervation of neuromuscular synapses persists well beyond this period in reeler mice (mutant mice lacking Reelin, a...

Reply to the Letter to the Editor: "A peripheral comment".

Comment on "Reelin promotes peripheral synapse elimination and maturation".

As the senior author of Quattrocchi et al. (1), I have attempted to reproduce the major findings described in this report in my laboratory, and to reconcile them with the findings of Bidoia et al. (2). Toward this end, I have reanalyzed the neuromuscular junction in the original reeler strain used for our study, and provided the mice to Misgeld, Lichtman, and Sanes [St. Louis, MO (2)] to rule o...

Peripheral ameloblastic fibro-odontoma in a cow

Tumours of odontogenic origin have been reported in various domestic animals. Ameloblastic fibroodontomais a rare tumour derived from odontogenic epithelium and pulpal mesenchyme. Plain andformalised sections from masses on the front of the cranial aspect of the jaw and the end of the tongue of acastrated beef cattle from an abattoir was submitted to Mt Pleasant laboratories, Launceston, Austra...

PERIPHERAL NEUROEPITHELIOMA: A STUDY OF EIGHT CASES

Peripheral neuroepitbelioma (PN) is a rare highly malignant tumor, classified in the group of small round cell tumors. We report eight cases of PN, based on histologic appearance and immunohistochemical staining for neuron-specific enolase (NSE). Electron microscopy was also performed in three cases. The tumors exhibited rapid local growth, leading to limb amputation in five cases. Histolo...